this route is mostly sealed the only unsealed parts is from cape tribulation to wujawujal. this parts is especially beatiful though.
you will have to cross a few creeks on this 35km stretch on gravel riad which might be unpassable in the wet season or after heavy rain.
about 40km north of port douglas you cross the daintree river by ferry and from there you are awaiting an about 60km long ride through the oldest living rainforest in the world.
near rossvile you are passing an old historical hotel with camping area and cabins. thus spot is definatly worth stopping.