This is a ride that will shows you the beauty and drastic differences in climate, vegetation, and altitude that is riding in Arizona. This a three day ride that requires riding 500 mile days to accomplish the full trip. If you have additional time you can cut the miles per day, but I live in Florida and tend to fly somewhere and rent a bike with unlimited mileage.
This is a fairly short run but it goes from desert all the way up to high alpine with great views. Nice long sweepers for a high speed run and the temp drops about 20-30 degrees from Vegas to the top of Mt. Charleston. FYI - Bring a jacket. Also there is a lodge at the top where you can grab lunch. If traveling to Vegas you don't want to miss this one.
Visiting Las Vegas? This is the loop to take the rental. This is a great run through the desert along Lake Mead. The corners are awesome and the scenery is really incredible. Stop at Echo Bay Resort for lunch then head over to the Valley of Fire State Park and bring the camera! Beautiful place. Your choice is head back the way you came or just scoot on back to Vegas down I15. I used to live in Vegas, this is a great loop for anyone.